|
NetTable 2. Localizations of S-ketamine-induced Increases (Anesthesia vs. Baseline) in
Regional Cerebral Blood Flow (rCBF). Absolute SPM-analysis (T = 8, k = 0). |
||||||||||||||
|
|
|
|
Proportion of |
|
Proportion of the Region |
|
Cluster |
|
Maximum Voxel |
|
Voxel |
|||
|
Lobe |
Region |
|
Cluster Volume (%) |
|
Covered by the Cluster (%) |
|
Voxels |
p |
|
MNI Coordinates |
|
p |
||
|
CLUSTER 1 |
|
|
|
|
|
|
789 |
< 0.001 |
|
-14 |
40 |
-16 |
|
0.001 |
|
Frontal Lobe |
Medial Frontal Gyrus |
R |
25.22 |
|
4.79 |
|
199 |
|
|
|
|
|
|
|
|
|
Medial Frontal Gyrus |
L |
11.53 |
|
2.29 |
|
91 |
|
|
|
|
|
|
|
|
Limbic Lobe |
Anterior Cingulate |
R |
14.32 |
|
7.08 |
|
113 |
|
|
|
|
|
|
|
|
Total % of the Cluster |
|
|
51.07 |
|
|
|
|
|
|
|
|
|
|
|
|
CLUSTER 2 |
|
|
|
|
|
|
5251 |
< 0.001 |
|
-66 |
-16 |
26 |
|
< 0.001 |
|
Frontal Lobe |
Precentral Gyrus |
L |
8.04 |
|
10.36 |
|
422 |
|
|
|
|
|
|
|
|
Temporal Lobe |
Transverse
Temporal Gyrus |
L |
2.8 |
|
60.25 |
|
147 |
|
|
|
|
|
|
|
|
|
Superior Temporal Gyrus |
L |
11.85 |
|
11.86 |
|
622 |
|
|
|
|
|
|
|
|
Parietal Lobe |
Inferior
Parietal Lobule |
L |
9.88 |
|
17.52 |
|
519 |
|
|
|
|
|
|
|
|
|
Postcentral Gyrus |
L |
20.21 |
|
35.2 |
|
1061 |
|
|
|
|
|
|
|
|
Insula |
|
L |
20.02 |
|
49.51 |
|
1051 |
|
|
|
|
|
|
|
|
Lentiform Nucleus |
|
L |
4.67 |
|
20.96 |
|
245 |
|
|
|
|
|
|
|
|
Claustrum |
|
L |
2.11 |
|
51.87 |
|
111 |
|
|
|
|
|
|
|
|
Thalamus |
|
L |
2.11 |
|
10.91 |
|
111 |
|
|
|
|
|
|
|
|
Total % of the Cluster |
|
|
81.69 |
|
|
|
|
|
|
|
|
|
|
|
|
CLUSTER 3 |
|
|
|
|
|
|
65 |
< 0.001 |
|
24 |
42 |
-14 |
|
0.002 |
|
Frontal Lobe |
Middle Frontal Gyrus |
R |
83.08 |
|
0.74 |
|
54 |
|
|
|
|
|
|
|
|
CLUSTER 4 |
|
|
|
|
|
|
5707 |
< 0.001 |
|
72 |
-32 |
24 |
|
< 0.001 |
|
Frontal Lobe |
Inferior Frontal Gyrus |
R |
1.79 |
|
2.18 |
|
102 |
|
|
|
|
|
|
|
|
|
Precentral Gyrus |
R |
11.34 |
|
15.92 |
|
647 |
|
|
|
|
|
|
|
|
Temporal Lobe |
Superior
Temporal Gyrus |
R |
10.23 |
|
11.12 |
|
584 |
|
|
|
|
|
|
|
|
|
Transverse Temporal Gyrus |
R |
2.44 |
|
58.65 |
|
139 |
|
|
|
|
|
|
|
|
Parietal Lobe |
Inferior
Parietal Lobule |
R |
8.66 |
|
16.73 |
|
494 |
|
|
|
|
|
|
|
|
|
Postcentral Gyrus |
R |
12.42 |
|
23.45 |
|
709 |
|
|
|
|
|
|
|
|
Insula |
|
R |
21.2 |
|
56.73 |
|
1210 |
|
|
|
|
|
|
|
|
Lentiform Nucleus |
|
R |
3.75 |
|
18.53 |
|
214 |
|
|
|
|
|
|
|
|
Claustrum |
|
R |
2.44 |
|
65.57 |
|
139 |
|
|
|
|
|
|
|
|
Total % of the Cluster |
|
|
74.27 |
|
|
|
|
|
|
|
|
|
|
|
|
CLUSTER 5 |
|
|
|
|
|
|
153 |
< 0.001 |
|
-52 |
40 |
12 |
|
0.001 |
|
Frontal Lobe |
Inferior Frontal
Gyrus |
L |
71.24 |
|
2.36 |
|
109 |
|
|
|
|
|
|
|
|
CLUSTER 6 |
|
|
|
|
|
|
213 |
< 0.001 |
|
52 |
50 |
2 |
|
0.001 |
|
Frontal Lobe |
Middle Frontal Gyrus |
R |
47.89 |
|
1.4 |
|
102 |
|
|
|
|
|
|
|
|
|
Inferior Frontal
Gyrus |
R |
34.74 |
|
1.58 |
|
74 |
|
|
|
|
|
|
|
|
Total % of the
Cluster |
|
|
82.63 |
|
|
|
176 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
CLUSTER 7 |
|
|
|
|
|
|
6036 |
< 0.001 |
|
-18 |
-28 |
44 |
|
< 0.001 |
|
Frontal Lobe |
Medial Frontal Gyrus |
R |
1.71 |
|
2.48 |
|
103 |
|
|
|
|
|
|
|
|
|
Medial Frontal Gyrus |
L |
3.79 |
|
5.75 |
|
229 |
|
|
|
|
|
|
|
|
Parietal Lobe |
Superior
Parietal Lobule |
R |
4.37 |
|
31.69 |
|
264 |
|
|
|
|
|
|
|
|
|
Superior
Parietal Lobule |
L |
2.07 |
|
14.92 |
|
125 |
|
|
|
|
|
|
|
|
|
Postcentral Gyrus |
R |
9.74 |
|
19.44 |
|
588 |
|
|
|
|
|
|
|
|
|
Postcentral Gyrus |
L |
7.39 |
|
14.8 |
|
446 |
|
|
|
|
|
|
|
|
|
Precuneus |
R |
2.93 |
|
4.58 |
|
177 |
|
|
|
|
|
|
|
|
|
Precuneus |
L |
2.93 |
|
4.79 |
|
177 |
|
|
|
|
|
|
|
|
|
Paracentral Lobule |
R |
5.67 |
|
44.3 |
|
342 |
|
|
|
|
|
|
|
|
|
Paracentral Lobule |
C |
1.26 |
|
78.35 |
|
76 |
|
|
|
|
|
|
|
|
|
Paracentral Lobule |
L |
9.56 |
|
83.38 |
|
577 |
|
|
|
|
|
|
|
|
Limbic Lobe |
Cingulate Gyrus |
R |
6.81 |
|
11.64 |
|
411 |
|
|
|
|
|
|
|
|
|
Cingulate Gyrus |
L |
3.61 |
|
6.84 |
|
218 |
|
|
|
|
|
|
|
|
Total % of the
Cluster |
|
|
61.84 |
|
|
|
3733 |
|
|
|
|
|
|
|
|
R = Right
Hemisphere, L = Left Hemisphere, C = Central, T = Height Threshold, k =
Extend Threshold. Unlocalized proportions were not
identifiable, located outside neural tissue or were sized < 50 voxels. |
||||||||||||||