|
NetTable 3. Localizations of S-ketamine-induced Increases (Anesthesia vs. Baseline) in
Regional Cerebral Metabolic Rate of Oxygen (rCMRO2). Absolute SPM-analysis (T = 3, k =
400). |
||||||||||||
|
|
|
|
Proportion of |
|
Proportion of the Region |
|
Cluster |
|
Maximum Voxel |
|||
|
Lobe |
Region |
|
Cluster Volume (%) |
|
Covered by the Cluster (%) |
|
Voxels |
p |
|
MNI Coordinates |
||
|
CLUSTER 1 |
|
|
|
|
|
|
31834 |
<0.001 |
|
-42 |
-44 |
-18 |
|
Frontal Lobe |
Precentral Gyrus |
R |
0.6 |
|
4.68 |
|
191 |
|
|
|
|
|
|
|
Inferior Frontal
Gyrus |
R |
2.1 |
|
14.33 |
|
669 |
|
|
|
|
|
|
|
Middle Frontal Gyrus |
L |
0.18 |
|
0.77 |
|
57 |
|
|
|
|
|
|
|
Middle Frontal Gyrus |
R |
2.63 |
|
11.51 |
|
837 |
|
|
|
|
|
|
|
Superior Frontal
Gyrus |
L |
0.47 |
|
2.59 |
|
150 |
|
|
|
|
|
|
|
Superior Frontal
Gyrus |
R |
1.96 |
|
10.64 |
|
624 |
|
|
|
|
|
|
|
Medial Frontal Gyrus |
R |
1.71 |
|
13.09 |
|
544 |
|
|
|
|
|
|
Paracentral Lobule |
|
R |
0.19 |
|
7.9 |
|
60 |
|
|
|
|
|
|
Parietal Lobe |
Inferior
Parietal Lobule |
R |
0.31 |
|
3.32 |
|
99 |
|
|
|
|
|
|
|
Superior
Parietal Lobule |
R |
0.24 |
|
9.12 |
|
76 |
|
|
|
|
|
|
|
Precuneus |
L |
0.8 |
|
6.9 |
|
255 |
|
|
|
|
|
|
|
Precuneus |
R |
0.83 |
|
6.84 |
|
264 |
|
|
|
|
|
|
|
Postcentral Gyrus |
R |
2.14 |
|
22.52 |
|
681 |
|
|
|
|
|
|
Temporal Lobe |
Transverse
Temporal Gyrus |
R |
0.3 |
|
39.66 |
|
96 |
|
|
|
|
|
|
|
Fusiform Gyrus |
L |
2.56 |
|
46.54 |
|
815 |
|
|
|
|
|
|
|
Fusiform Gyrus |
R |
0.85 |
|
15.46 |
|
271 |
|
|
|
|
|
|
|
Middle Temporal Gyrus |
L |
0.62 |
|
3.91 |
|
197 |
|
|
|
|
|
|
|
Middle Temporal Gyrus |
R |
1.37 |
|
8.71 |
|
436 |
|
|
|
|
|
|
|
Superior Temporal Gyrus |
R |
3.53 |
|
21.42 |
|
1124 |
|
|
|
|
|
|
Occipital Lobe |
Inferior
Occipital Gyrus |
L |
1.19 |
|
52.87 |
|
379 |
|
|
|
|
|
|
|
Inferior
Occipital Gyrus |
R |
0.73 |
|
32 |
|
232 |
|
|
|
|
|
|
|
Middle Occipital
Gyrus |
L |
1.32 |
|
16.87 |
|
420 |
|
|
|
|
|
|
|
Middle Occipital
Gyrus |
R |
1.55 |
|
19.69 |
|
493 |
|
|
|
|
|
|
|
Lingual Gyrus |
L |
1.84 |
|
27.32 |
|
586 |
|
|
|
|
|
|
|
Lingual Gyrus |
R |
1.58 |
|
22.82 |
|
503 |
|
|
|
|
|
|
|
Cuneus |
L |
0.8 |
|
8.95 |
|
255 |
|
|
|
|
|
|
|
Cuneus |
R |
2.44 |
|
26.3 |
|
777 |
|
|
|
|
|
|
Limbic Lobe |
Anterior Cingulate |
R |
1.52 |
|
30.37 |
|
484 |
|
|
|
|
|
|
|
Subcallosal Gyrus |
R |
0.28 |
|
30.82 |
|
89 |
|
|
|
|
|
|
|
Uncus |
R |
0.41 |
|
19.85 |
|
131 |
|
|
|
|
|
|
|
Inferior
Temporal Gyrus |
L |
0.94 |
|
21.85 |
|
299 |
|
|
|
|
|
|
|
Inferior Temporal Gyrus |
R |
1.21 |
|
28.22 |
|
385 |
|
|
|
|
|
|
Insula |
|
R |
0.77 |
|
11.44 |
|
245 |
|
|
|
|
|
|
Lentiform Nucleus |
|
R |
0.19 |
|
5.37 |
|
60 |
|
|
|
|
|
|
Anterior Lobe of Cerebellum |
Culmen |
L |
0.22 |
|
2.71 |
|
70 |
|
|
|
|
|
|
Posterior Lobe
of Cerebellum |
Declive |
L |
1.28 |
|
18.21 |
|
407 |
|
|
|
|
|
|
|
Declive |
R |
0.63 |
|
8.89 |
|
201 |
|
|
|
|
|
|
|
Tuber |
L |
0.52 |
|
13.01 |
|
166 |
|
|
|
|
|
|
|
Tuber |
R |
0.22 |
|
5.33 |
|
70 |
|
|
|
|
|
|
Total % of the Cluster |
|
|
43.0 |
|
|
|
13698 |
|
|
|
|
|
|
CLUSTER 2 |
|
|
|
|
|
|
1686 |
<0.001 |
|
16 |
-42 |
0 |
|
Limbic Lobe |
Posterior Cingulate |
L |
5.46 |
|
9.91 |
|
92 |
|
|
|
|
|
|
|
Posterior Cingulate |
R |
23.78 |
|
39.59 |
|
401 |
|
|
|
|
|
|
|
Parahippocampal Gyrus |
L |
4.8 |
|
3.95 |
|
81 |
|
|
|
|
|
|
|
Parahippocampal Gyrus |
R |
9.85 |
|
8.2 |
|
166 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Thalamus |
|
R |
6.7 |
|
11.11 |
|
113 |
|
|
|
|
|
|
Total % of the Cluster |
|
|
50.6 |
|
|
|
853 |
|
|
|
|
|
|
CLUSTER 3 |
|
|
|
|
|
|
827 |
0.006 |
|
-62 |
-18 |
-6 |
|
Parietal Lobe |
Postcentral Gyrus |
L |
23.46 |
|
6.44 |
|
194 |
|
|
|
|
|
|
Temporal Lobe |
Middle Temporal Gyrus |
L |
8.34 |
|
1.38 |
|
69 |
|
|
|
|
|
|
|
Superior
Temporal Gyrus |
L |
22.73 |
|
3.59 |
|
188 |
|
|
|
|
|
|
|
Transverse Temporal Gyrus |
L |
9.55 |
|
32.38 |
|
79 |
|
|
|
|
|
|
Insula |
|
L |
23.7 |
|
9.23 |
|
196 |
|
|
|
|
|
|
Total % of the Cluster |
|
|
87.8 |
|
|
|
726 |
|
|
|
|
|
|
CLUSTER 4 |
|
|
|
|
|
|
723 |
0.013 |
|
-40 |
0 |
6 |
|
Frontal? Lobe |
Precentral Gyrus |
L |
7.19 |
|
1.28 |
|
52 |
|
|
|
|
|
|
|
Inferior Frontal Gyrus |
L |
27.39 |
|
4.29 |
|
198 |
|
|
|
|
|
|
Temporal Lobe |
Superior Temporal Gyrus |
L |
16.46 |
|
2.27 |
|
119 |
|
|
|
|
|
|
Insula |
|
L |
37.07 |
|
12.62 |
|
268 |
|
|
|
|
|
|
Total % of the
Cluster |
|
|
88.1 |
|
|
|
637 |
|
|
|
|
|
|
R = Right
Hemisphere, L = Left Hemisphere, T = Height Threshold, k = Extend Threshold. Unlocalized proportions were not identifiable, located
outside neural tissue or were sized < 50 voxels. |
||||||||||||